RNA修復機構がヒトで偶然に起こった
RNA ligase mechanism and identification of C12orf29 by chemical proteomics using modified Ap3A probe. a Schematic display of the three-step mechanism of RNA ligation by a 5′–3′ RNA ligase. In step 1, the ligase is auto-AMPylated on the catalytic lysine using ATP as the co-substrate. In step 2, the AMP is transferred from the catalytic…